KAIST Proposes New Parkinson's Treatment Strategy through Discovery of RNA Editing Enzyme Role
Creatrip Team
a year ago
Researchers from KAIST in South Korea, collaborating with England's UCL National Hospital for Neurology and Neurosurgery and Francis Crick Institute, have discovered that the RNA editing enzyme ADAR1 plays a crucial role in controlling neuroinflammation, a key pathology in Parkinson’s disease. Using stem cell-derived models from Parkinson’s patients, they observed that the ADAR1 enzyme modulates immune responses by editing RNA, suggesting a potential new target for treatment. This groundbreaking research, demonstrating abnormal RNA editing as a factor in chronic inflammation and disease progression, was published in 'Science Advances.'
